Focus on the Endogenous Cannabinoid System in Migraine

  • Home / Focus on the Endogenous Cannabinoid System in Migraine

Focus on the Endogenous Cannabinoid System in Migraine

*Domenico Chirchiglia, Attilio Della Torre, Pasquale Chirchiglia

Department of Neurosurgery, Neurophysiopathology Unit, University of Catanzaro, Catanzaro, Italy
*Correspondence to chirchiglia@unicz.it

Disclosure: The authors have declared no conflicts of interest.
Received: 13.01.17 Accepted: 22.05.17
Citation: EMJ Neurol. 2017;5[1]:88-91.

Abstract

Migraine prophylaxis represents a better choice than symptomatic drugs, both for safety and for effectiveness. Today, drugs such as calcium channel blockers, beta-blockers, and topiramate are still used to treat migraine with and without aura, often with satisfactory results but in some cases with adverse effects, thus limiting their use. A new class of drugs in migraine prophylaxis are endocannabinoids, substances which modulate the mechanisms of neuroinflammation that cause migraine pain. Anandamide and palmitoylethanolamide have proven useful in migraine prophylaxis, suggesting their influence in neuroinflammatory processes and opening the way for new therapeutic perspectives.

This article is made available under the terms of the Creative Commons Attribution-Non Commercial 4.0 License.

The post Focus on the Endogenous Cannabinoid System in Migraine appeared first on European Medical Journal.

About Post Author

Medical CPD & News

The Digitalis CPD trawler searches the web for all the latest news and journals.

Privacy Preference Center

Close your account?

Your account will be closed and all data will be permanently deleted and cannot be recovered. Are you sure?

Are you sure?

By disagreeing you will no longer have access to our site and will be logged out.